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Common side effects may include: Mild to moderate nausea Occasional vomiting Constipation or irregular bowel movements Diarrhea General abdominal discomfort or stomach pain Excessive burping and bloating In addition to these, some users have reported more serious or rare adverse reactions, such as: Pancreatitis (inflammation of the pancreas) Gallbladder-related issues, including gallstones Acute kidney injury in sensitive individuals Ozempic face (facial volume loss or sagging) Allergic reactions (rash, itching, or swelling) Changes in mood or behavior, including signs of depression Suicidal thoughts or ideation (seek immediate medical help if experienced) Higher risk of aspiration during procedures involving sedation or anesthesia Increased risk of thyroid tumors, such as medullary thyroid carcinoma (MTC) has been observed in rodent studies

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The intestinal immunoendocrine axis: novel cross-talk between enteroendocrine cells and the immune system during infection and inflammatory disease