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Some proteins upregulated in pts with ALT increases (e.g., CXCL10, CXCL9, IL10) were also found to be associated with timing of ALT increase in the previous Phase 2a study (NCT02981602)
In heart failure, non-coding RNAs, particularly miRNAs encapsulated in extracellular vesicles (EV), influence the redox balance in the myocardium and brain by regulating the NRF2 signaling pathway
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Neuroscience 551, 3142
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