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It estimated that a $150 monthly cap could unlock access for up to 15 million Americans when applied to orforglipron, its experimental weight-loss pill that succeeded in a late-stage trial
Tsukamoto et al
The STEP-HFpEF trial randomised 529 patients with obesity (BMI 30 kg/m 2 ), HFpEF (left ventricular ejection fraction [LVEF] 45%) and New York Heart Association (NYHA) Class II symptoms to once-weekly subcutaneous semaglutide 2.4 mg or placebo
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