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The prolonged exposures to dietary TMAO or choline resulted in a significant increase in plasma cystatin C levels in mice, indicating renal dysfunction (Tang et al., 2015b)
This has not been confirmed in humans, but as a precaution, neither drug should be used by people with a personal or family history of medullary thyroid cancer (MTC) or a rare genetic condition called MEN2
Smooths dry patches
These medications have also shown potential in slowing CKD progression and reducing hypoglycemia risks (6)
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