A randomized controlled trial by Matteo Tosato and et.al
biological function 2016 Distribution of glutathione and glutathione-related enzyme systems in mitochondria and cytosol of cultured cerebellar astrocytes and granule cells.1995 One gene two localization in mitochondria and cytosol Tom70 enhances mitochondrial preprotein import efficiency by binding to internal targeting sequences 2018 Enzymes Cell signaling and Ligand transport Structural proteins REGULATION DIAGNOSTIC USE Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration 2018 The plant mitochondrial import machinery
Most excluded studies examined glutathione in specific clinical contexts (melasma treatment, postinflammatory hyperpigmentation) rather than addressing general skin health in aging populations
The composition according to Claim 1, wherein the triazine alcohol heterocyclic ring compound is chosen from l-[3,5-Bis(2-hydroxyethyl)-l,3,5- triazinan-l-yl]-2-propanol, l,3,5-Triazine-l,3,5(2H,4H,6H)-triethanol, a- methyl-, l,3,5-triazine-l,3,5(2H,4H, 6H)- triethanol, l,3,5trihydroxyethylhexahydrotraiazine, 1,3,5-Tris(2- hydroxyethyl)hexahydro- 1 ,3,5-triazine, 1 ,3,5-Tris(2- hydroxyethyl)hexahydro-s-triazine, 2,2',2"-(Hexahydro-l,3,5-triazine-l,3,5- triyl)triethanol, 2-[4,6-bis(2-hydroxyethyl)-l,3,5-triazinan-2-yl]ethanol, s- Triazine-l,3,5(2H,4H,6H)-triethanol, Triazinetriethanol