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In wound healing, for example, combined scRNA-seq and spatial transcriptomic analyses demonstrated that dysfunctional Spp1 + macrophages in aged individuals suppress type II immune responses, thereby impairing extracellular matrix-mediated repair of epidermal cells and fibroblasts (327)
Frias, J.P
10.1093/nar/gkp970 71 QiuY.BenetL
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