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GLP-1 plays a crucial role in glucose homeostasis by stimulating insulin secretion from pancreatic beta cells in a glucose-dependent manner, suppressing glucagon release, and slowing gastric emptying
N Engl J Med 326:13161322
Besides deamination and 15N NH 4 + production 15N labeled glutamate can be converted to 15N labeled amino acids, most prominently alanine, via transamination reactions (Figure 1, )
As weight loss medication becomes more common in Australia, awareness of these interactions is increasingly important
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