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Foods to minimize or avoid include: Carbonated beverages, which introduce additional gas High-fiber foods initially (beans, cruciferous vegetables, whole grains), though fiber remains important long-term Artificial sweeteners, particularly sugar alcohols (sorbitol, xylitol), which can ferment in the gut Dairy products if lactose intolerance is present or suspected Fried or greasy foods that slow digestion Hydration remains essential, but patients should sip water throughout the day rather than consuming large volumes with meals, which can increase stomach distension

Starting at lower doses and increasing more slowly often produces better long-term compliance with fewer side effects

Angiotensin-converting enzyme 2 (ACE2) expression increases with age in patients requiring mechanical ventilation