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Description

Because SO286 binds to STI1 regions that mediate the liquidgel/solid transition of UBQLN2 droplets by promoting self-interaction and oligomerization (Dao et al, 2018), we speculated that SO286 may inhibit the liquidgel/solid transition of UBQLN2 droplets by competitively inhibiting the STI1-mediated self-interaction of UBQLN2

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