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So far, beverage giants have downplayed the effect of GLP-1 drugs on their portfolios: pointing to the work theyve already done in building up low and no calorie options over the last couple of decades

For the person with type 2 diabetes at high risk of CV disease (primary prevention), consider: Adding in (or substituting) an SGLT2 inhibitor with known CV benefit (canagliflozin, empagliflozin, dapagliflozin)

The cost difference is negligible, typically a few dollars per box of 100, and the accuracy improvement is meaningful

The FDA briefing documents reflect this pattern of front-loaded side effects that resolve with continued use