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At the transcriptional level, many of the genes whose expression is altered in NAFLD such as genes regulating lipid synthesis (eg, acetyl-CoA carboxylase 1 , fatty acid synthase , diacylglycerol o-acyltransferase) and mitochondrial -oxidation (eg, long-chain acyl-CoA dehydrogenase , hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha , UCP2 , acyl-CoA oxidase ) are upregulated, potentially as a secondary compensatory mechanism to respond to the increased flow of substrate due to calorie overload
Epidermal Inclusion Cysts (Sebaceous Cysts) Also called epidermoid cysts, these are pockets of keratin and skin cells trapped beneath the skin
Investigators, not participants, managed escalation and interruption
