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The trial used a three-week dose-escalation schedule, raising the daily amount in steps to the full 500 mg, which the authors used to limit early gut symptoms [4]
The dose can be further increased to 1 mg weekly and up to 2 mg weekly if needed for optimal glycaemic control, depending on individual response and tolerability
Is Mounjaro stronger than Wegovy
This was confirmed in 1987, when GLP-1 was identified as an incretin hormone and shown to be more effective than GIP in stimulating insulin release on a molar basis, at an equivalent level of glycaemia [2]
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