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doi:10.1001/jama.2026.0287 To view or add a comment, sign in Mechanistic Comparison of Single, Dual, and Triple Incretin-Based Agonists The progressive mechanistic complexity and metabolic efficacy of modern incretin-based therapies, moving from single to dual and triple receptor agonism

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These patients are typically better served by NAD+ first, with GHK-Cu added once the bioenergetic foundation is addressed