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Although no clinical trial has yet evaluated the effect of glitazone therapy on skeletal muscle mass or strength in humans as a standalone therapy, pioglitazone has been tested as an adjunctive therapy in older people with impaired physical function undergoing a weight loss programme

But most people find it takes at least a few weeks before they notice a change in their appetite and body weight

For one thing, prescribing it for weight loss only is off-label, and therefore viewed by insurance companies as off-plan.) Nevertheless, last October, Twitter and Tesla titan Elon Musk announced he was taking Wegovy on where else, Twitter