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While definitive mechanisms remain uncertain, research suggests that the peptide's interaction with melanocortin receptors may be examined for its potential role in maintaining metabolic equilibrium
Because both drugs can affect the stomach and brain, the cumulative effect can be more noticeable initially
Pharmacokinetic and endpoint data from human studies does not transfer to an in vitro system or to a rodent model, and the receptor-level measurements that do transfer are a small fraction of the total citation volume
doi:10.1210/endo.140.1.6398
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