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Possible Side Effects and Considerations While Tirzepatide is generally well-tolerated, some users may experience: Nausea Mild digestive discomfort Fatigue These side effects usually fade as your body adjusts to the medication
Cortisol and stress hormones Caloric restriction elevates cortisol
These additional GIP-related research dimensions make both compounds valuable across broader investigational frameworks than purely metabolic studies
While caloric restriction is therapeutically desired for weight loss, excessive reduction or poor nutritional quality can result in fatigue, weakness, and decreased stamina
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