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Capsules were packaged in 28 mL pill bottles, each containing four pomegranate capsules (400 mg each) or four placebo capsules, along with 3 500 mg L-carnitine (Carnipure ) capsules (VitaminExpress LLC, Irvine, CA, USA) and a silica gel sachet
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additionally, alcar raised the transcription of grm2 gene encoding for the mglu2 receptor via increasing the levels of acetylated h3k27 bound to the grm2 promoter and gaining the acetylation of nf-kb-p65 subunit
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