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[252] Healthcare providers can help develop appropriate discontinuation strategies based on individual circumstances
To date, tirzepatide has demonstrated CV safety when compared with pooled comparators in a meta-analysis of phase 2 and phase 3 studies with the hazard ratio of 0.80 (95% CI: 0.571.11) for MACE-4 [24]
Clin Toxicol 48:613 Du X, Edelstein D, Obici S, Higham N, Zou MH, Brownlee M (2006) Insulin resistance reduces arterial prostacyclin synthase and eNOS activities by increasing endothelial fatty acid oxidation
Methods: We collected plasma samples and clinical data from 494 individuals with hyperlipidemia
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