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Jacalyn Sieben, ND Sources: Friedman, S
SUGGESTED DAILY USE: Take two (2) capsules daily, with or without food, or as directed by your healthcare professional
Genotoxicity of haloalkene and haloalkane glutathione S-conjugates in porcine kidney cells [PMID: 20702313] Laboratory literature summary: Genotoxicity of haloalkene and haloalkane glutathione S-conjugates in porcine kidney cells
Similar to cagrilintide, pramlintide is primarily eliminated via the kidneys and, in a pharmacokinetic study in participants with type 1 diabetes, no statistically significant differences were noted in total (AUC 0- ) and peak ( C max ) exposure after administration of a single pramlintide 60 g dose in participants with mild, moderate or severe renal impairment compared with those with normal renal function, although inter-patient variability was high [20]
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