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Such emergencies should be treated as follows: As an initial goal, reduce mean arterial pressure (MAP) by no more than 25% within minutes to hours
Low dose proved to be no better than a placebo but a higher dose is being tested
As most RCTs were designed to evaluate metabolic or cardiovascular outcomes rather than cancer endpoints, their follow-up periods may be insufficient to fully capture the latency of solid tumor development
Nevertheless, minimizing light exposure extends shelf life
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