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Comparing the Side Effects of Tirzepatide and Semaglutide While both drugs have been generally well-tolerated in clinical trials, there are some side effects associated with their use
In many cases, what happens is: finish your current cycle of tirzepatide (or reduce to a stable dose), then after a defined interval (often one week or so) begin retatrutide at the low dose under provider monitoring
Science (1979) 373 , eabe4832 (2021)