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During injury states, this balance shifts to strongly elevate NOS2 expression specifically in healing contexts
[6] Because NAD + -dependent enzymes are involved in DNA repair, protein deacetylation, stress responses, mitochondrial function, and cellular signaling, NNMT-related changes in NAD + availability should be interpreted in a pathway-specific manner rather than as a simple beneficial-or-harmful binary
With IV drugs that can cause a metallic taste, the side effect may occur within seconds or minutes of injection
Wu J, Rosen BP (1993) Metalloregulated expression of the Ars operon
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