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Calcium chelators: Calcium binds to tetracyclines, which form complexes that inhibit absorption and efficacy of antibiotics
The injectable requires subcutaneous injection, starting at a low dose of 0.25 mg weekly for the first four weeks and gradually increasing the dosage monthly
DPP4 needs dimerization for enzymatic activity, and this is the predominant form of DPP4 ( The serine in the active site of DPP4 is located in the sequence GlyTrpSerTyrGly and is part of the catalytic triad (Ser 630, Asp 708, His 740) within the catalytic region of DPP4
For short-term storage, standard refrigeration (2C to 8C) is acceptable
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