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It combines GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) agonism
This step limits the metabolic rate of FAs and is regulated by the concentration of malonyl coenzyme A (malonyl-CoA)
The peptide has also been shown to be equally as potent at stimulating melanogenesis as the related, FDA-approved peptide called afemelanotide (MT-I) [1]
These deficiencies dont cause psoriatic arthritis on their own for sure, but they make the inflammation causing it louder, the pain even more stronger, and recovery slower
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