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Description

Although these structures provide molecular insights into diverse activation mechanisms of these three receptors, it remains unclear whether an extracellular agonist is required for G protein coupling and downstream signal transduction

Front Cell Dev Biol 12, 1460697

Lilly's phase 2 trial looked at 338 adults who were obese or overweight and were randomized to receive a placebo or one of four dosages of retatrutide