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From a safety perspective, gastrointestinal adverse effects are the most commonly reported for GLP-1 RAs, with nausea, vomiting, and diarrhea remaining the leading causes of treatment discontinuation [7]

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Genetic Predispositions and Peptide Pathway Response Variation Clinical research identifies specific genetic variants in GIPR, and MC4R genes that correlate with GLP-1 response profiles

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Biochem J 417:113

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PMID: 34 KaracabeyliDLacailleD

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