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10.1038/mt.2012.232 49 MilicV
Different macronutrients stimulate GLP-1 secretion to varying degrees: Fiber and complex carbohydrates : Dietary fiber, particularly soluble fiber, enhances GLP-1 secretion by slowing nutrient absorption and allowing more prolonged contact with L-cells in the distal intestine
The approval by the FDA also clears the pill for usage to reduce the risk of major cardiovascular events like death, heart attack, or stroke in adults having obesity and established cardiovascular disease, says Novo Nordisk
The xenobiotic adaptation in arthropods evolves through multiple mechanisms (Figure 1) [13, 14], including reduced penetration through the cuticle, behavioral avoidance [15, 16], microbiome-mediated detoxification [17-20], enhanced metabolic detoxification [21-25], enhanced sequestration or excretion [13, 19, 26, 27], and target site insensitivity [28-32]
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