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However, it remains out of reach for patients who are unwilling or unable to self-administer a weekly injection
The fact that covering GLP-1s under Medicare Part D for authorized uses is already making a mark on total Part D program spending could be a sign of even higher spending to come as Part D plans are now able to cover Wegovy for its heart health benefits, as other uses for GLP-1s are approved, and as policymakers consider legislation that would authorize Medicare to cover obesity drugs
The scale is different, but the math works the same way
A 2021 study tracking substrate oxidation in fasted subjects found that peptide agonists administered during the cortisol peak increased fat oxidation by 1822% compared to evening dosing, sustained across an 8-hour measurement window
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