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reported a prevalence of 20.5% among Indian males.[] It is more common in Fitzpatrick skin types IV, V and VI namely the Hispanic, Caribbean and Asian races as they live in areas exposed to intense ultraviolet (UV) radiation resulting in larger amounts of melanin production.[] In India, melasma is the most common pigmentary disorder, with an incidence of approximately 10%;[] often developing at a younger age having strong correlation with positive family history, thus, supporting the role of genetic factors in its development.[] Although the exact pathogenesis is unknown, dysfunctional melanogenesis plays a pivotal role

To our knowledge, there is no evidence that DAMPs might be released in eryptosis, and this lethal subroutine of erythrocytes elicits DAMP-associated immunogenic consequences