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Insulin resistance and chronic hyperglycemia cause a cascade of pathological events in the brain, including neuroinflammation, impaired neurotransmitter systems and energy metabolism, oxidative stress, and vascular pathologies that ultimately lead to neurodegeneration, loss of synaptic plasticity, brain aging, cognitive impairment, and dementia

They release cytokines like transforming growth factor-beta (TGF-) and IL-10, which help resolve inflammation and promote tissue repair and remodeling [82]

And it is essential to remember that any medication for weight loss should be prescribed and monitored by a qualified physician like Dr

Frequently Asked Questions How does the article separate the titration phase from the maintenance phase