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They affect amyloidosis through their role in the synthesis and disposal of A, as well as through interactions with other CNS cells (Frost and Li, 2017)
Ferroptosis mediated by the interaction between Mfn2 and IREalpha promotes arsenic-induced nonalcoholic steatohepatitis
Read review Dihexa for Endometriosis Brain Fog The November 2025 Lancet O&G/WH 'overlooked symptom' commentary from Edinburgh EXPPECT, the April 2025 Horn FACT-Cog 1,239-patient survey (~80% perceived cognitive impairment), the March 2025 NICE TA1057 Ryeqo approval (first daily pill on NHS), the April 2024 NICE NG73 update, the April 2026 renewed Womens Health Strategy with 117 action points, the 2023 Greaves CNS-wide glial activation mouse model, the BDNF/TrkB central-sensitisation directionality paradox, and the ~1.5 million UK women affected
Biol Psychiatry 97:11271138
