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Rotating Injection Sites and Best Practices Systematic rotation of injection sites is crucial for preventing lipohypertrophy (thickening of fatty tissue) and lipoatrophy (loss of fatty tissue), both of which can impair medication absorption and lead to unpredictable blood glucose control

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Ishikawa T, Terai N, Sato R, et al

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I would imagine people gain some weight back and that there is like the holidays and things like that

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The typical dose for weight loss is 2.4 milligrams, administered weekly as subcutaneous (under the skin) self-injections

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