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The clinical trials supporting GLP-1 medications didn't include antioxidant supplementation, and post-market real-world data hasn't identified oxidative stress as a limiting factor in treatment outcomes

Adipocyte energy expenditure published animal models have explored NNMT inhibition with 5-Amino-1MQ in diet-induced-obesity rodents, examining adipose-tissue mass, energy expenditure, and metabolic markers

Selenium Se contributes to important biological processes like prevention of DNA damage, energy metabolism in membrane integrity, antioxidant role, and redox regulation [157]