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Once internalized, these agents can engage and disrupt critical oncogenic pathways for example, suppressing phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/ mechanistic target of rapamycin (mTOR) signaling, inhibiting Wnt/-catenin activation or perturbing deoxyribonucleic acid (DNA) damage repair networks thereby inducing apoptosis or sensitizing cancer cells to subsequent therapy
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Additionally, a published study found that cancer patients who drank whey protein had higher levels of glutathione in their bodies, while cruciferous vegetables, such as broccoli and cauliflower, have also been found to support glutathione production
Although early combination therapy may increase initial costs, it has the potential to reduce long-term healthcare expenditures by lowering the need for interventions and hospitalizations [127,128]
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