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Sherman CB: Health effects of cigarette smoking

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The MDM2 inhibitor nutlin-3a suppresses abnormal T-cell expansion and reduces systemic inflammation in SLE models, highlighting an immunoregulatory role for MDM2 inhibition beyond oncology

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No participants developed antibodies against the peptide, and no serious adverse events led to treatment withdrawal

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However, the link between iron loading and macrophage polarization exhibits context dependence

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