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It carries long-chain fatty acids into structures inside cells called mitochondria, where those fats can be broken down and used as fuel
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8 For example, in NSCLC, COL11A1 CAFs accumulate at tumor margins, deposit dense ECM components (COL1A1, COL3A1), and physically restrict CD8 T-cell infiltration by interacting with tumor DDR1
Lilly has submitted orforglipron for approval in more than 40 countries
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