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It is commonly employed in longevity and age-related signaling models, where researchers examine endpoints such as gene expression patterns, cellular stress responses, and telomere-related pathways in preclinical or in vitro systems

doi: 10.1016/j.jjcc.2011.01.007

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Pro-inflammatory cytokines similarly link autophagy to apoptosis and have been shown to be associated with neuropathic pain (138), This phenomenon suggests that we may be able to further explore whether there are pro-inflammatory cytokine-related drugs to treat neuropathic pain in DPN patients by improving the apoptosis and autophagy link