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[12] There are several theoretical concerns with combining these agents: Cardiovascular effects : Both substances may influence heart rate and blood pressure, potentially leading to additive effects that could be problematic for individuals with hypertension, arrhythmias, or other cardiovascular conditions

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Prenatal alcohol exposure, which is classified as a teratogen, can damage the brain across a continuum of gross to subtle impairments, depending on the amount, timing, and frequency of the exposure as well as genetic predispositions of the fetus and mother