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It has been reported that these three compounds can enhance the contents of GSH and the activities of GSH-dependent antioxidant enzymes (GPX and GST) and reduce lipid peroxidation and cardiac damage mediated by DOX or isoproterenol (ISO) in the myocardium of rats, respectively [121, 129, 130]

The first to become available on the market was Byetta (exenatide), which was approved for the management of type 2 diabetes in 2005

Melatonin synthesis: multiplicity of regulation [PMID: 1685290] Laboratory literature summary: Melatonin synthesis: multiplicity of regulation

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