The elevation in the Ang I/Ang II ratio could be related to decreased production of Ang II, due to reduced angiotensin-converting enzyme (ACE) activity, or increased degradation of Ang II, either by ACE type 2 or, as recently suggested, by peptidases, such as dipeptidyl peptidase 3 (DPP3) [8, 11,12,13]
Understanding this phase as potentially positive rather than concerning helps maintain protocol adherence
This is especially good news if your skin is prone to: Redness or flushing Post-treatment sensitivity Chronic irritation or reactivity Barrier breakdown or dryness With regular use, GHK-Cu can help interrupt the inflammation cycle and lay the groundwork for long-term skin health
From a formulation perspective, Inspira Skins emphasis on medical-grade serums aligns very well with categories such as peptide serums, regenerative skincare, and post-procedure recovery products