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While B12 is naturally present in animal-based foods such as meat, fish, and dairy, many people struggle to get adequate amounts due to dietary restrictions, absorption issues, or certain medical conditions
Oral B12 supplements have to pass through the gut, and absorption can be limited especially if you have digestive issues, take certain medications like metformin or antacids, or simply have low stomach acid
Published rodent and cell-culture work has examined NNMT inhibition in the context of adipocyte metabolism and of methyl-donor and NAD pool dynamics
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