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In recent years, glucagon-like peptide-1 receptor agonists (GLP-1 RAs) have emerged as effective therapeutic agents, as they stimulate insulin secretion and suppress glucagon release in a glucose-dependent manner, thereby improving glycemic control with a low risk of hypoglycemia [2]
A retrospective cohort study found that semaglutide use was associated with a 44% reduced risk of incident cannabis use disorder (CUD) in patients with no prior history (hazard ratio [HR]: 0.56, 95% confidence interval [CI]: 0.420.75) and a 38% reduction in recurrent CUD diagnosis (HR: 0.62, 95% CI: 0.460.84) among patients with a prior history, compared to non-GLP-1RA medications [Citation61]
I., Svensson, C
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