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Description

Amgens investigational maridebart caftaglutide (Maritide) targets the GLP-1 receptor and glucose-dependent insulinotropic polypeptide receptor (GIPR)

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In the kidney, GLP-1RAs directly induce natriuresis and diuresis by acting on the proximal convoluted tubule (PCT) through inhibition of sodium-hydrogen exchanger 3 (NHE3)

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What other nutrients are depleted by GLP-1 medications

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First-line medications for neuropathic pain and allodynia include the following options

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