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Complicating the matter, administration of ghrelin still leads to cross-desensitization of dopamine-induced Ca 2+ mobilization, and while ghrelin antagonism also reduces this mobilization, it is possible that concurrent cross-sensitization may also occur, which may possibly carry beyond the timeframe of bioavailability of such an antagonist
European journal of medical research, 13 (2), 7378
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Both are dominated by dose-related gastrointestinal effects (nausea, diarrhea, constipation)
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