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the human evidence is at the level of outcomes (people ate less and lost weight), not mechanism
It is also beneficial and may have neuroprotective effects
That is the evidence gap, stated plainly: the mechanism is well-motivated and the preclinical signal is consistent, but no human study has confirmed that any of it translates to people, at any dose, by any route
Over the last few years, a dramatic surge in patient utilization has been observed across advanced domestic sports medicine networks
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