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These recommendations are based on results that showed that GLP-1RA compared with insulin therapy (basal, premixed, or intensified basal-bolus regimens) have similar or even better efficacy in HbA1c reduction and a lower hypoglycemia risk, promotes weight loss instead of weight gain, and reduces the burden of drug administration frequency and self-monitoring of blood glucose [1, 2]

There is slower migration of fibroblasts and wound-healing cells to these sites of injury owing to the poor blood supply, and therefore the repair process is obstructed

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For L6-GLUT4myc cells, differentiation was initiated at 8090% confluence using -MEM supplemented with 2% horse serum (HS), refreshed every 23 days