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In research settings, it is used to study multi-hormonal metabolic pathways, peptidereceptor signaling, and mechanisms related to energy balance and nutrient regulation

TSH-controlled L-thyroxine therapy reduces cholesterol levels and clinical symptoms in subclinical hypothyroidism: A double blind, placebocontrolled trial (Basel Thyroid Study)

Combined treatment with BET and IGF-IR pathway inhibitors achieves potent and durable response in preclinical models [139]

These DSBs are usually repaired by homologous directed repair (HDR) or nonhomologous end joining (NHEJ), achieving mutation or foreign gene insertion (Fig