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Oxidation, or oxidative stress and the subsequent reactive oxygen species (ROS) and reactive nitrogen species (RNS) increases tremendously when we become injured, when we have an infection (such as a flu virus, gingivitis, Epstein Barr virus, Herpes virus, etc.) and/or inflammation, such as from leaky gut and food sensitivities

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This work was supported by the National Natural Science Foundation of China (81501006 and 81400950)

A century later, in 1776, Matthew Dobson, an English physician in Liverpool, discovered that when the urine of diabetic patients evaporated it left behind a sugar-like substance