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on the contrary, it is dispersed heterogeneously, mainly as single cells, along the epithelium of the GI tract, from the stomach to the rectum with a defined cephalocaudal, crypt-to-villus in the small intestine and crypt-to-surface distribution in the colon ( Despite representing just 1% of the adult gut epithelium, in the last decade it has become clear that the EECs constitute the largest endocrine organ in mammalia ( Collectively, the EECs are responsible for the production of more than 30 different hormones that help to orchestrate the fate of the intermediary metabolism

Murray-Thomas T, Cruz JM, Harder-Lauridsen NM, Olsen AH, Williams R, Major-Pedersen A

However, the theoretical risk exists, and researchers with a history of pancreatitis or heavy alcohol use should exercise particular caution

It is designed to support repair signaling, inflammation control, collagen remodeling, and tissue organization