CBO points out that the studies we have on this topic rely on correlations between [body mass index (BMI)] and health conditions and between health conditions and health care spending, which may or may not be driven by a causal relationship. As CBO notes, there is a correlation between higher BMIs and higher health care spending
they may also dampen its response
According to the Summary of Product Characteristics (SmPC) approved by the MHRA, nausea is very common (may affect more than 1 in 10 people), whilst vomiting, diarrhoea, abdominal pain, and constipation are common (may affect up to 1 in 10 people)
A few studies also suggest that GLP-1 RAs may increase fertility in men, particularly those with obesity, by improving semen concentration, motility, and morphology